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A multicenter study for the detection and the development of nationwide reporting system of toxic liver injury
ABSTRACT - A hundred ten toxic liver injury cases were newly detected from May to October 2005 in 17 university hospitals. Blood samples was collected from 108 cases of reported for SNP study. Etiologies of enrolled cases included herb medicine(33.6%), conventional drugs(28.2%), health food(11.8%), folk remedy(5.5%) and others(20.0%) in order. The most common seller or prescribing person of causative food or drugs was a herbalist(28.2%). The frequency of hepatitis type, mixed type, and cholestatic type according to R value were 95 cases (86.4%), 12 cases (10.9%), and 3 cases (2.7%), respectively. The mean RUCAM score was 7.0¡¾1.7. Nine cases(8.2%) were proven to be absolute, 68 cases(61.8%) were scored to be probable. On the other hand, another multi-center study was performed to develop investigating method of medical cost for health in Korean. This study revealed that total medical cost associated with health in each Korean patient(including conventional medicine, Oriental medicine, health food, etc) was 502 thousands won. The expenditure of patients who used oriental medicine to it was 420 thousands won.
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